STUDY ON THE EFFECT OF TILETAMINE-ZOLAZEPAM AND KETOFOL IN CONJUCTION WITH GLYCOPYRROLATE, PENTAZOCINE-LACTATE AND MIDAZOLAM ON CLINICO-PHYSIOLOGICAL PARAMETERS IN DOGS.

Abstract

Current research was carried out for studies on the comparative evaluation of ketofol and tiletamine-zolazepam in conjunction with glycopyrrolate, pentazocine-lactate and midazolam for surgical intervention in dogs. The animals were separated into two distinct groups, having  six animals each. Dogs were premedicated in both groups with glycopyrrolate @0.01 mg/kg b.wt I/M. and after 05 minutes pentazocine lactate @ 2 mg /kg bwt I/V and midazolam @ 0.5 mg /kg b.wt I/V. In group I animals were induced and maintained with tiletamine-zolazepam @ 6.5 mg/kg b.wt I/V and in group II, animal were induced and maintained with ketofol @ 4 mg/kg b.wt I/V. Heart rate after administration of anaesthesia increased non-significanlty in group I and II. Respiration rate increased significantly after induction in group I and non-significantly in group II. Non-significant decrease in rectal temperature after induction was observed in both the groups. SpO2% decreased significantly in group I and II. An initial increase in MAP  was observed in group I and II.