STUDIES ON EFFICACY OF AUTOLOGOUS PLATELET-RICH FIBRIN GEL FOR WOUND HEALING IN BOVINE

Abstract

Platelet-rich fibrin gel has condensed growth factors and cytokines, known to be used in various dental and orthopedic procedures for its better healing efficacy. Present study was conducted on 12 bovines having clinical wound reported to Teaching Veterinary Clinical Complex (TVCC), College of Veterinary Science and Animal Husbandry, Rewa. The animals were randomly divided into two groups having 6 animals each. Wound of group I was treated by topical application of APRF on 0th, 5th, 10th, and 15th day post-treatment. Wounds of group II acted as control and were treated with Normal Saline Solution. The wounds were evaluated on the basis of gross appearance, exudation, pain at the site on 0th 5th, 10th, 15th and 20th post-treatment day and wound contraction rate on 5th, 10th, 15th, 20th and 25th post treatment day. Respective intensity of colour and moisture of both the groups were in descending order on 10th day of evaluation. Wounds of control groups were mild moist and moderate pink; however, intensity was clearly faint and wounds were dry in appearance APRF group. No pain was manifested by any animal of group I on 15th post-treatment day however, it was still present in some of the animals of control group.. Wound contraction on 15th post treatment day in group I was 87.82 percent as compared to 37.27 percent in control group.